FlyBase Allele Report: Dmel\eIF1A[BH167]

General Information

Symbol

Dmel\eIF1A^BH167

Species

D. melanogaster

Name

FlyBase ID

FBal0301166

Feature type

allele

Associated gene

Dmel\eIF1A

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Li et al., 2014)

Progenitor genotype

Cytology

Description

Nucleotide substitution: C109T.

(Li et al., 2014)

Amino acid replacement: Q37term.

(Li et al., 2014)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:18,275,046..18,275,046 [+]

Nucleotide change:

C18275046T

Reported nucleotide change:

C109T

Amino acid change:

Q37term | eIF1A-PA; Q37term | eIF1A-PB; Q37term | eIF1A-PC

Reported amino acid change:

Q37term

(Li et al., 2014)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Li et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

eIF1A^BH167/eIF-1A[+] is a suppressor of visible phenotype of spn-A^093A/spn-A³

(Li et al., 2014)

eIF1A^BH167/eIF-1A[+] is a suppressor of visible phenotype of spn-B^BU

(Li et al., 2014)

Phenotype Manifest In

Suppressor of

Statement

Reference

eIF1A^BH167/eIF-1A[+] is a suppressor of egg chorion phenotype of spn-A^093A/spn-A³

(Li et al., 2014)

eIF1A^BH167/eIF-1A[+] is a suppressor of egg chorion phenotype of spn-B^BU

(Li et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

eIF-1A^BH167 dominantly suppresses the eggshell patterning defects in spn-A³/spn-A^093A mutants.

eIF-1A^BH167 dominantly suppresses the eggshell patterning defects in spn-B^BU mutants.

(Li et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

eIF-1A^BH167

eIF1A^BH167

(Li et al., 2014)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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