FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DetS125A.GFP
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General Information
Symbol
Dmel\DetS125A.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0301292
Feature type
allele
Associated gene
Dmel\Det
Associated Insertion(s)
Carried in Construct
P{Det-GFP.S125A}
Key Links
Transgenic product class
missense_variant
(Mathieu et al., 2013)
polypeptide_post_translational_processing_variant
(Mathieu et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Mathieu et al., 2013)
polypeptide_post_translational_processing_variant
(Mathieu et al., 2013)
Mutagen
in vitro construct
(Mathieu et al., 2013)
Progenitor genotype
Carried in construct
P{Det-GFP.S125A}
Cytology
Description

Amino acid replacement: S125A.

(Mathieu et al., 2013)

A genomic fragment containing the Det promoter and Det coding region fused at the C-terminal with GFP. This transgene contains an amino acid residue mutation that destroys a putative phosphorylation site.

(Mathieu et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
Det
Encoded product / tool
Det
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      DetS125A.GFP partially rescues Det2180

      (Mathieu et al., 2013)
      Comments

      The presence of DetS125A.T:Avic\GFP rescues viability and diploidy in Det2180. However, the number of germline cells per egg chamber is not rescued.

      (Mathieu et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DetS125A.GFP
      DetS125A.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)