FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Wnt5unspecified
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General Information
Symbol
Dmel\Wnt5unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0301549
Feature type
allele
Associated gene
Dmel\Wnt5
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The ventral antennal lobe is poorly innervated by projection neuron dendrites in homozygous adults, due to displacement of the ventral projection neuron dendrites to the dorsal region of the antennal lobe. This defect is due to a failure of the normal ventromedial migration of the projection neuron dendrites during the pupal stage.

        (Wu et al., 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        Wnt5[+]/Wnt5unspecified is an enhancer of abnormal neuroanatomy | adult stage phenotype of drlunspecified

        (Wu et al., 2014)
        Suppressor of
        Statement
        Reference

        Wnt5[+]/Wnt5unspecified is a suppressor of abnormal neuroanatomy | adult stage phenotype of drlunspecified

        (Wu et al., 2014)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Wnt5unspecified/+ largely suppresses the dendritic targeting defects of homozygous drlunspecified adPN, lPN and vPN projection neuron clones, while the penetrance of the DL1 mistargeting phenotype is slightly increased.

        (Wu et al., 2014)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Not rescued by

        Wnt5unspecified is not rescued by Scer\GAL4peb-GAL4/Wnt5UAS.cFa

        (Wu et al., 2014)
        Comments

        Expression of Wnt5Scer\UAS.cFa under the control of Scer\GAL4peb-GAL4 fails to rescue antennal lobe development in Wnt5unspecified animals.

        (Wu et al., 2014)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Wnt5unspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (2)