FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CSN4UASp.Tag:HA
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General Information
Symbol
Dmel\CSN4UASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0301604
Feature type
allele
Associated gene
Dmel\CSN4
Associated Insertion(s)
Carried in Construct
P{UASp-CSN4.HA}
Key Links
Transgenic product class
wild_type
(Pan et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Pan et al., 2014)
Mutagen
in vitro construct
(Pan et al., 2014)
Progenitor genotype
Carried in construct
P{UASp-CSN4.HA}
Cytology
Description

UASp regulatory sequences drive expression of CSN4 tagged with Tag:HA.

(Pan et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
CSN4
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of CSN4Scer\UAS.P\T.T:Ivir\HA1 in the germline under the control of Scer\GAL4nos.PU has no effect on cystoblast and two cell cyst number in the ovary compared to wild type controls. Germline stem cell number is also unaffected.

      (Pan et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of CSN4Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4nos.PU in a bamΔ86/+ mutant background results in an increase in cystoblast and two cell cyst number in the ovary compared to controls. Germline stem cell number is unaffected.

      Expression of CSN4Scer\UAS.P\T.T:Ivir\HA1 in the germline under the control of Scer\GAL4nos.PU partially suppresses the germline stem cell (GSC) loss seen upon expression of bamhs.PO. 65% of germaria retain GSCs, compared to 83-95% when bamhs.PO is expressed alone.

      (Pan et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CSN4Scer\UAS.P\T.T:Ivir\HA1
      CSN4UASp.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)