UAS regulatory sequences are followed by a Cep290 fragment containing the promoter and entire gene region up to the last codon. The coding sequence is tagged at the C-terminal end with GFP.
cep290-GFP localizes to the transition zone at the tip of the mother centriole in Drosophila sensory cilia. It is also present in the spermatocyte primary cilium and at the base of the spermatid ciliary cap.