FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cep2900153-G4
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General Information
Symbol
Dmel\Cep2900153-G4
Species
D. melanogaster
Name
FlyBase ID
FBal0317877
Feature type
allele
Associated gene
Dmel\Cep290
Associated Insertion(s)
PBac{IT.GAL4}Cep2900153-G4
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Clandinin and Owens, 2016-)
Progenitor genotype
Associated Insertion(s)
PBac{IT.GAL4}Cep2900153-G4
Cytology
Description

The PBac{IT.GAL4}cep2900153-G4 insertion maps within the cep290 gene.

(Clandinin and Owens, 2016-)
Allele components
Component
Use(s)
Inserted element
PBac{IT.GAL4}
Encoded product / tool
GAL4
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      cep2900153-G4 individuals are severely uncoordinated. Their spermatid cysts are disorganized and with dispersed nuclei, associated with axonemal elongation defects. Most spermatids also exhibit aberrant growth of axonemal microtubules.

      (Lapart et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cep2900153-G4
      (Lapart et al., 2019)
      cep2900153-G4
      Name Synonyms
      Secondary FlyBase IDs
        References (2)