FlyBase Allele Report: Dmel\mir-1010[KO]

General Information

Symbol

Dmel\mir-1010^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0301894

Feature type

allele

Associated gene

Dmel\mir-1010

Associated Insertion(s)

TI{TI}mir-1010^KO

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

ends-out gene targeting

(Chen et al., 2014)

FLPase

(Chen et al., 2014)

I-SceI

(Chen et al., 2014)

cre recombinase

(Chen et al., 2014)

Progenitor genotype

Associated Insertion(s)

TI{TI}mir-1010^KO

Cytology

Description

The 8bp miRNA seed sequence of the mir-1010 miRtron has been deleted. A single loxP site is present at the site of the deletion. The expression of the SKIP host gene appears unaffected (assayed by quantitative PCR).

(Chen et al., 2014)

Allele components

Component

Use(s)

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female fertile

(Chen et al., 2014)

female fertile (with Df(3R)Exel6190)

(Chen et al., 2014)

male fertile

(Chen et al., 2014)

male fertile (with Df(3R)Exel6190)

(Chen et al., 2014)

partially lethal (with Df(3R)Exel6190)

(Chen et al., 2014)

some die during embryonic stage | maternal effect (with Df(3R)Exel6190)

(Chen et al., 2014)

some die during embryonic stage | recessive | maternal effect | recessive

(Chen et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

58886

w^*; TI{TI}mir-1010^KO/TM3, P{GAL4-twi.G}2.3, P{UAS-2xEGFP}AH2.3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

MiR-1010^KO

(Amourda and Saunders, 2020)

mir-1010^KO

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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