FB2025_05 , released December 11, 2025
Allele: Dmel\ScrUAS.cPb
Open Close
General Information
Symbol
Dmel\ScrUAS.cPb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Percival-Smith
FlyBase ID
FBal0301960
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
P{UAS-Scr.Pb}
Key Links
Transgenic product class
wild_type
(Percival-Smith et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Percival-Smith et al., 2013)
Mutagen
in vitro construct
(Percival-Smith et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-Scr.Pb}
Cytology
Description

UAS regulatory sequences drive expression of full-length Scr.

(Percival-Smith et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Scr
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ScrScer\UAS.cPb under the control of Scer\GAL4rn.PU results in strong induction of ectopic sex combs on both the second and third legs.

      Expression of ScrScer\UAS.cPb under the control of Scer\GAL4arm.PU results in ectopic T1 beards and salivary glands. Ectopic tarsi are seen when ScrScer\UAS.cPb is expressed under the control of Scer\GAL4dpp.PU.

      Expression of ScrScer\UAS.cPb under the control of Scer\GAL4pb.PJ does not result in an antenna to proboscis transformation, either at room temperature or higher temperatures.

      (Percival-Smith et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of ScrScer\UAS.cPb and pbScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4pb.PJ does not result in an antenna to proboscis transformation. The antenna is transformed to maxillary palp, as in seen when pbScer\UAS.T:Avic\GFP-EGFP is expressed alone.

      Expression of ScrScer\UAS.cPb under the control of Scer\GAL4pb.PJ in a pb27/pb20 mutant background results in a normal antenna.

      Expression of ScrScer\UAS.cPb under the control of Scer\GAL4pb.PJ does not suppress the vestigial maxillary palp phenotype seen in pb27/pb20 mutant flies.

      (Percival-Smith et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ScrScer\UAS.cPb
      ScrUAS.cPb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Percival-Smith
      Secondary FlyBase IDs
        References (1)