FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4VGlut1.PC
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General Information
Symbol
Scer\GAL4VGlut1.PC
Species
S. cerevisiae
Name
FlyBase ID
FBal0302102
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{VGlut1-GAL4.C}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cassar et al., 2015)
Progenitor genotype
Carried in construct
P{VGlut1-GAL4.C}
Cytology
Description

A 5.5 kb genomic fragment containing regulatory sequences from VGlut is fused upstream to GAL4. This fragment includes 3.6 kb upstream the VGlut transcription start site and the 5'-untranslated coding sequence with the first two introns of the gene.

(Cassar et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
VGlut1
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Activation of Scer\GAL4VGlut.PC-expressing glutamatergic neurons (GNs) for two hours results in increased resistance to paraquat intoxication. Survival levels following direct application of paraquat to the ventral nerve cord (VNC) of decapitated flies are significantly reduced compared with unactivated controls. Most flies survive GN activation in the absence of paraquat. Neuromuscular junction function is unaffected.

      (Cassar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4VGlut.PC
      Scer\GAL4VGlut1.PC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)