FB2026_02 , released June 18, 2026
Allele: Dmel\pnutK288A.pnut.Tag:FLAG
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General Information
Symbol
Dmel\pnutK288A.pnut.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0302774
Feature type
allele
Associated gene
Dmel\pnut
Associated Insertion(s)
Carried in Construct
P{pnut.FLAG.K288A}
Key Links
Transgenic product class
missense_variant
(Akhmetova et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Akhmetova et al., 2015)
Mutagen
in vitro construct
(Akhmetova et al., 2015)
Progenitor genotype
Carried in construct
P{pnut.FLAG.K288A}
Cytology
Description

A mutant pnut cDNA is expressed under the control of a 1.7 kb native pnut promoter fused with N-terminal Tag:FLAG. The mutant polypeptide carries amino acid substitution K288A.

(Akhmetova et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
pnut
Encoded product / tool
pnut
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      pnutK288A.pnut.Tag:FLAG partially rescues pnutXP

      (Akhmetova et al., 2015)
      Comments

      pnutK288A.pnut.T:Zzzz\FLAG fails to rescue the lethality of pnutXP. However, the cytokinesis defects associated with pnutXP are rescued. Imaginal disc development is also rescued by pnutK288A.pnut.T:Zzzz\FLAG.

      (Akhmetova et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pnutK288A.pnut.T:Zzzz\FLAG
      pnutK288A.pnut.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)