FlyBase Allele Report: Dmel\Cad99C[UAS.GFP]

General Information

Symbol

Dmel\Cad99C^UAS.GFP

Species

D. melanogaster

Name

FlyBase ID

FBal0302863

Feature type

allele

Associated gene

Dmel\Cad99C

Associated Insertion(s)

Carried in Construct

P{UAS-Cad99C.GFP.L}

Also Known As

UAS-Cad99C-GFP

Key Links

Transgenic product class

wild_type

(Lee et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Lee et al., 2015)

Mutagen

in vitro construct

(Lee et al., 2015)

Progenitor genotype

Carried in construct

P{UAS-Cad99C.GFP.L}

Cytology

Description

UAS regulatory sequences drive expression of Cad99C tagged with GFP.

(Lee et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Cad99C

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has endosome | adult stage phenotype, suppressible by Traf-like^Δ/Traf-like^Δ

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has adult enterocyte phenotype, suppressible by Traf-like^Δ/Traf-like^Δ

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has endosome | adult stage | conditional phenotype, suppressible by Traf-like^Δ/Traf-like^Δ

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has adult enterocyte | conditional phenotype, suppressible by Traf-like^Δ/Traf-like^Δ

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has endosome | adult stage phenotype, suppressible by nopo^Exc142/nopo^Exc142

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has adult enterocyte phenotype, suppressible by nopo^Exc142/nopo^Exc142

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has endosome | adult stage phenotype, suppressible by Uev1A^KK110298/Scer\GAL4^GSG5966

(Lee et al., 2018)

Cad99C^UAS.GFP, Scer\GAL4^NP0001 has adult enterocyte phenotype, suppressible by Uev1A^KK110298/Scer\GAL4^GSG5966

(Lee et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

The Scer\GAL4^NP0001>Cad99C^UAS.GFP-induced Cad99C^UAS.GFP-positive endosome formation in adult enterocytes is abolished by Traf-like^Δ homozygosity and enhanced either by nopo^Exc142 homozygosity or by the expression of Uev1A^KK110298 under the control of Scer\GAL4^GSG5966 (and RU486 feeding); the enhanced endosome formation upon Ecc15 enteric infection is also abolished by Traf-like^Δ homozygosity.

(Lee et al., 2018)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Cad99C^{Scer\UAS.T:Avic\GFP}

Cad99C^UAS.GFP

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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