FlyBase Allele Report: Dmel\ap[DG11]

General Information

Symbol

Dmel\ap^DG11

Species

D. melanogaster

Name

FlyBase ID

FBal0304935

Feature type

allele

Associated gene

Dmel\ap

Associated Insertion(s)

Carried in Construct

Also Known As

Df(2R)ap^DG11

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - genetic evidence

Mutagen

FLPase

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Bieli et al., 2015)

Mutagen

FLPase

(Bieli et al., 2015)

Progenitor genotype

P{(-loxP)(-FRT)Flipper2}ap^MM

(Bieli et al., 2015)

ap^DD35.34

(Bieli et al., 2015)

Cytology

Description

An approximately 11-kb deletion between two FRT sites located in P{(-loxP)(-FRT)Flipper2}ap^MM and ap^DD35.34.

(Bieli et al., 2015)

A deletion that removes the apC wing enhancer.

(Bieli et al., 2015)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2R:5,727,233..5,738,472 [-]

Comment:

Scer\FRT-mediated recombination between the two progenitor insertions has deleted ~11 kb of sequence between them.

(Bieli et al., 2015)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible (with ap^DG3)

(Bieli et al., 2015, Bieli et al., 2015)

Phenotype Manifest In

haltere (with ap^DG3)

(Bieli et al., 2015)

wing (with ap^DG3)

(Bieli et al., 2015, Bieli et al., 2015)

Detailed Description

Statement

Reference

ap^DG11/ap^DG3 flies lack all wing and haltere structures.

(Bieli et al., 2015)

No wings are seen in ap^DG11/ap^DG3 mutant flies.

(Bieli et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

ap^blt

(Bieli et al., 2015)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Df(2R)ap^DG11

(Bieli et al., 2015, Bieli et al., 2015)

ap^DG11

(Bieli et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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