FlyBase Allele Report: Dmel\Erk7[UAS.Tag:V5,Tag:polyHis]

General Information

Symbol

Dmel\Erk7^{UAS.Tag:V5,Tag:polyHis}

Species

D. melanogaster

Name

FlyBase ID

FBal0305050

Feature type

allele

Associated gene

Dmel\Erk7

Associated Insertion(s)

Carried in Construct

P{UAS-Erk7.V5.His}

Key Links

Transgenic product class

cDNA

(Hasygar and Hietakangas, 2014)

wild_type

(Hasygar and Hietakangas, 2014)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Hasygar and Hietakangas, 2014)

wild_type

(Hasygar and Hietakangas, 2014)

Mutagen

in vitro construct

(Hasygar and Hietakangas, 2014)

Progenitor genotype

Carried in construct

P{UAS-Erk7.V5.His}

Cytology

Description

UASt regulates expression of an Erk7 cDNA tagged with Tag:V5 and Tag:polyHis.

(Hasygar and Hietakangas, 2014)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

fat cell | somatic clone, with Scer\GAL4^Cg.PA

(Hasygar et al., 2021)

lipid droplet | decreased number | somatic clone, with Scer\GAL4^Cg.PA

(Hasygar et al., 2021)

nucleolus | somatic clone, with Scer\GAL4^Act.PU

(Hasygar et al., 2021)

nucleus | somatic clone, with Scer\GAL4^Act.PU

(Hasygar et al., 2021)

Detailed Description

Statement

Reference

Scer\GAL4^Ilp2.PR-mediated, but not Scer\GAL4^Sgs3.PD-mediated expression results in delayed pupation and a significant reduction in pupal volume compared to controls.

(Hasygar and Hietakangas, 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Erk7^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^Cg.PA has abnormal developmental rate phenotype, suppressible by sug^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^Cg.PA

(Hasygar et al., 2021)

Erk7^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^Cg.PA has decreased body size | P-stage phenotype, suppressible by sug^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^Cg.PA

(Hasygar et al., 2021)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Erk7^{Scer\UAS.T:SV5\V5,T:Zzzz\His6}

Erk7^{UAS.Tag:V5,Tag:polyHis}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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