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General Information
Symbol
Dmel\DnaJ-1UAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Takeuchi
FlyBase ID
FBal0305147
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a DnaJ-1 cDNA (GH26396).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of DnaJ-1Scer\UAS.cTa in photoreceptors under the control of Scer\GAL4GMR.PU suppresses the eye degeneration seen in flies expressing Hsap\HTTGMR.Q120.

Expression of DnaJ-1Scer\UAS.cTa in the pigment cells under the control of Scer\GAL454C partially suppresses the eye degeneration seen in flies expressing Hsap\HTTGMR.Q120. There is a significant increase in the number of rhabdomeres per ommatidium compared to Hsap\HTTGMR.Q120 alone. Expression under the control of another pigment cell driver, Scer\GAL4rdhB.PW, also suppresses the degeneration, and this suppression can be canceled out by co-expressing Ykt6dsRNA.Scer\UAS.cUa.

Expression of DnaJ-1Scer\UAS.cTa in either muscle (under the control of Scer\GAL4Mef2.PU or Scer\GAL4Mhc.PU) or fat body (using Scer\GAL4Lsp2.PH or Scer\GAL4r4) partially suppresses the photoreceptor degeneration seen in Hsap\HTTGMR.Q120 mutant flies.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
DnaJ-1Scer\UAS.cTa
DnaJ-1UAS.cTa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Takeuchi
Secondary FlyBase IDs
    References (1)