FlyBase Allele Report: Dmel\Cip4[RNAi.UAS.cUa]

General Information

Symbol

Dmel\Cip4^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0314804

Feature type

allele

Associated gene

Dmel\Cip4

Associated Insertion(s)

Carried in Construct

P{UAS-Cip4.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Cip4.RNAi.U}

Cytology

Description

UAS regulates expression of an RNAi construct targeting Cip4.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Cip4

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell size, with Scer\GAL4^ap.PU

(Zobel et al., 2015)

Phenotype Manifest In

adherens junction, with Scer\GAL4^ap.PU

(Zobel et al., 2015)

wing hair | increased number, with Scer\GAL4^en.PU

(Zobel et al., 2015)

Detailed Description

Statement

Reference

Scer\GAL4^en.PU-mediated expression of Cip4^{dsRNA.Scer\UAS.cUa} results in ~10% of cells having duplicate wing hairs.

Scer\GAL4^ap.PU-mediated expression of Cip4^{dsRNA.Scer\UAS.cUa} results in the formation of tubular shg-positive vesicles at adherens junctions and increases cell size.

(Zobel et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Cip4^RNAi.UAS.cUa, Scer\GAL4^ap.PU has increased cell size phenotype, non-enhanceable by Nost^RNAi.UAS.cUa, Scer\GAL4^ap.PU

(Zobel et al., 2015)

Other

Statement

Reference

Cip4^RNAi.UAS.cUa, Nost^RNAi.UAS.cUa, Scer\GAL4^en.PU has abnormal cell shape phenotype

(Zobel et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Cip4^RNAi.UAS.cUa, Scer\GAL4^en.PU has wing hair | increased number phenotype, enhanceable by Nost^RNAi.UAS.cUa, Scer\GAL4^en.PU

(Zobel et al., 2015)

Cip4^RNAi.UAS.cUa, Scer\GAL4^ap.PU has adherens junction phenotype, enhanceable by Nost^RNAi.UAS.cUa, Scer\GAL4^ap.PU

(Zobel et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Scer\GAL4^en.PU-mediated co-expression of Cip4^{dsRNA.Scer\UAS.cUa} and Nost^{dsRNA.Scer\UAS.cUa} results in disrupted ridges and misshaped cells in the adult wing.

(Zobel et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Cip4^RNAi.UAS.cUa

Cip4^{dsRNA.Scer\UAS.cUa}

Cip4^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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