FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\chinmoHMC05346
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General Information
Symbol
Dmel\chinmoHMC05346
Species
D. melanogaster
Name
FlyBase ID
FBal0315131
Feature type
allele
Associated gene
Dmel\chinmo
Associated Insertion(s)
Carried in Construct
P{TRiP.HMC05346}
Also Known As
UAS-chinmo-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HMC05346}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMC05346
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Individuals expressing chinmoHMC05346 under the control of Scer\GAL4en-e16E arrest as L1 larvae, despite growing larger than control L2 larvae. Some of these larvae assume a "tiger-striped" appearance, with two thin rings of tanned cuticle within each segmental en expression domain; epidermal cells between en domains make a new, L2 cuticle, while cells within each en domain do not and instead start puparium tanning. The expression domain within the larval salivary gland presents nuclei that fail to grow. The expression domain within the wing disc shows abnormally thickened and disorganized cells.

      (Truman and Riddiford, 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      chinmoHMC05346
      Name Synonyms
      Secondary FlyBase IDs
        References (6)