FlyBase Allele Report: Dmel\smo[HMJ30064]

General Information

Symbol

Dmel\smo^HMJ30064

Species

D. melanogaster

Name

FlyBase ID

FBal0315889

Feature type

allele

Associated gene

Dmel\smo

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ30064}

Also Known As

smoKD

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HMJ30064}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ30064

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

egg chamber, with Scer\GAL4^c306

(Dai et al., 2017)

ovariole, with Scer\GAL4^c306

(Dai et al., 2017)

Detailed Description

Statement

Reference

The expression of smo^HMJ30064 under the control of Scer\GAL4^c306 leads to a severe increase in the proportion of ovarioles showing fused egg chambers, as compared to controls.

(Dai et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^c306, smo^HMJ30064 has egg chamber phenotype, enhanceable by dsh^JF01253/Scer\GAL4^c306

(Dai et al., 2017)

Scer\GAL4^c306, smo^HMJ30064 has ovariole phenotype, enhanceable by dsh^JF01253/Scer\GAL4^c306

(Dai et al., 2017)

Scer\GAL4^c306, smo^HMJ30064 has egg chamber phenotype, enhanceable by dsh^JF01254/Scer\GAL4^c306

(Dai et al., 2017)

Scer\GAL4^c306, smo^HMJ30064 has ovariole phenotype, enhanceable by dsh^JF01254/Scer\GAL4^c306

(Dai et al., 2017)

Enhancer of

Statement

Reference

Scer\GAL4^c306/smo^HMJ30064 is an enhancer of egg chamber phenotype of Scer\GAL4^c306, dsh^JF01253

(Dai et al., 2017)

Scer\GAL4^c306/smo^HMJ30064 is an enhancer of ovariole phenotype of Scer\GAL4^c306, dsh^JF01253

(Dai et al., 2017)

Scer\GAL4^c306/smo^HMJ30064 is an enhancer of egg chamber phenotype of Scer\GAL4^c306, dsh^JF01254

(Dai et al., 2017)

Scer\GAL4^c306/smo^HMJ30064 is an enhancer of ovariole phenotype of Scer\GAL4^c306, dsh^JF01254

(Dai et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of smo^HMJ30064 and either dsh^JF01253 or dsh^JF01254 (under the control of Scer\GAL4^c306) leads to a more severe egg-fusion phenotype than the corresponding single expression conditions.

(Dai et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

62987