FlyBase Allele Report: Dmel\wgn[KO]

General Information

Symbol

Dmel\wgn^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0316442

Feature type

allele

Associated gene

Dmel\wgn

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

ends-in gene targeting

(Andersen et al., 2015)

FLPase

(Andersen et al., 2015)

I-SceI

(Andersen et al., 2015)

Progenitor genotype

Cytology

Description

Ends-in gene targeting event resulting in frameshift mutations in exon 1 and 2.

(Andersen et al., 2015)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

insertion

X:18,628,617..18,628,618 [-]

Comment:

wgn^KO was created by an ends-in gene targeting event that introduced frameshift mutations in exon 1 and 2. The second frameshift is an insertion of four bases.

(Andersen et al., 2015)

insertion

X:18,629,169..18,629,170 [-]

Comment:

wgn^KO was created by an ends-in gene targeting event that introduced frameshift mutations in exon 1 and 2. The first frameshift is an insertion of two bases.

(Andersen et al., 2015)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

wgn^KO is a non-suppressor of neoplasia phenotype of Scer\GAL4^rn-GAL4-5, crb^intra.UAS

(Andersen et al., 2015)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

wgn^KO is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, egr^UAS.cMa, grnd^KK109939

(Andersen et al., 2015)

wgn^KO is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, egr^UAS.cMa

(Andersen et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

wgn^K0

(Loudhaief et al., 2023)

wgn^KO

(Loudhaief et al., 2023, Muzzopappa et al., 2017, Andersen et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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