FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Vap33+tMa
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General Information
Symbol
Dmel\Vap33+tMa
Species
D. melanogaster
Name
FlyBase ID
FBal0316819
Feature type
allele
Associated gene
Dmel\Vap33
Associated Insertion(s)
Carried in Construct
P{Vap33.WT}
PBac{Vap33.WT}
Also Known As
gVAPWT
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Moustaqim-Barrette et al., 2014)
wild_type
(Moustaqim-Barrette et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Moustaqim-Barrette et al., 2014)
wild_type
(Moustaqim-Barrette et al., 2014)
Mutagen
in vitro construct
(Moustaqim-Barrette et al., 2014)
Progenitor genotype
Carried in construct
P{Vap33.WT}
PBac{Vap33.WT}
Cytology
Description

Wild-type genomic fragment that includes Vap-33A.

(Moustaqim-Barrette et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
Vap33
Encoded product / tool
Vap33
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
X:3,945,705..3,955,520 [+]
Comment:

Extent of rescue fragment determined from reported primer sequences.

(Moustaqim-Barrette et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Vap33+tMa rescues Vap33Δ31

      (Moustaqim-Barrette et al., 2014)

      Vap33+tMa rescues Vap33Δ31/Vap33ALS8

      (Moustaqim-Barrette et al., 2014)
      Comments

      Vap-33A+tMa rescues the lethality of Vap-33AΔ31 animals and significantly restores lifespan. The giant fiber neuron defects are also rescued.

      Vap-33A+tMa rescues the lethality, reduced lifespan, progressive flight defects and central nervous system defects seen in Vap-33AΔ31 ; Vap-33AALS8 animals.

      (Moustaqim-Barrette et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Vap-33A+tMa
      Vap33+tMa
      gVAPWT
      (Tendulkar et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)