FB2026_02 , released June 18, 2026
Allele: Dmel\Xport-BΔB
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General Information
Symbol
Dmel\Xport-BΔB
Species
D. melanogaster
Name
FlyBase ID
FBal0316834
Feature type
allele
Associated gene
Dmel\Xport-B
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Chen et al., 2015)
Mutagen
gene targeting by homologous recombination
(Chen et al., 2015)
Progenitor genotype
Cytology
Description

0.3kb deletion that removes the entire Xport-B coding sequence. While the deletion eliminates expression of the Xport-B protein, Xport-A protein is still expressed in Xport-BΔB mutants.

(Chen et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:19,914,483..19,914,822 [-]
Comment:

~0.3 kb deletion generated by homologous recombination gene targeting. Deletion extent inferred from primer sequences.

(Chen et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant adults show only a transient electroretinogram response to light, in contrast to the sustained response seen in wild-type flies.

      Mutant adults show severe retinal degeneration at 14 days of age (raised under light:dark conditions).

      (Chen et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Xport-BΔB has abnormal neurophysiology | adult stage phenotype, enhanceable by trplMB10553

      (Chen et al., 2015)
      NOT suppressed by
      Statement
      Reference

      Xport-BΔB has abnormal neurophysiology | adult stage phenotype, non-suppressible by Xport-AninaE.PC

      (Chen et al., 2015)
      NOT Enhancer of
      Statement
      Reference

      Xport-BΔB is a non-enhancer of abnormal neurophysiology | adult stage phenotype of trpMB03672

      (Chen et al., 2015)
      NOT Suppressor of
      Statement
      Reference

      Xport-BΔB is a non-suppressor of abnormal neurophysiology | adult stage phenotype of trpMB03672

      (Chen et al., 2015)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Xport-AninaE.PC does not rescue the electroretinogram defects of Xport-BΔB adults.

      The electroretinogram defects seen in trpMB03672 flies are not altered if the flies are also mutant for Xport-BΔB.

      trplMB10553 enhances the electroretinogram defects seen in Xport-A1, Xport-BΔB flies.

      (Chen et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Xport-BΔB is rescued by Xport-BninaE.PC

      (Chen et al., 2015)

      Xport-BΔB is rescued by Xport-BninaE.Tag:SBP

      (Chen et al., 2015)
      Comments

      Expression of Xport-BninaE.PC or Xport-BninaE.T:Zzzz\SBP rescues the electroretinogram defects of Xport-BΔB adults.

      (Chen et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Xport-BΔB
      xportΔB
      (Chen et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)