FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\trplMB10553
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General Information
Symbol
Dmel\trplMB10553
Species
D. melanogaster
Name
FlyBase ID
FBal0240023
Feature type
allele
Associated gene
Dmel\trpl
Associated Insertion(s)
Mi{ET1}trplMB10553
Carried in Construct
Also Known As
trpl29134, trplMB
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{ET1}trplMB10553
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{ET1}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        trplMB10553 is an enhancer of abnormal neurophysiology | adult stage phenotype of Xport-A1

        (Chen et al., 2015)

        trplMB10553 is an enhancer of abnormal neurophysiology | adult stage phenotype of Xport-BΔB

        (Chen et al., 2015)
        Suppressor of
        Statement
        Reference

        trplMB10553/trplMB10553 is a suppressor of abnormal circadian rhythm | adult stage phenotype of cry01, norpAP24

        (Ni et al., 2017)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Additional homozygosity for trplMB10553 rescues the circadian rhythmicity defects observed in cry01, norpA36 double homozygous adults previously trained under 12h:12h light:dark cycles.

        (Ni et al., 2017)

        trplMB10553 enhances the electroretinogram defects seen in Xport-A1, Xport-BΔB and Df(3R)Xport-ΔAB flies. trplMB10553 ; Df(3R)Xport-ΔAB flies are almost unresponsive to light.

        (Chen et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        References (14)