FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\PPO31
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General Information
Symbol
Dmel\PPO31
Species
D. melanogaster
Name
FlyBase ID
FBal0316883
Feature type
allele
Associated gene
Dmel\PPO3
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    336bp deletion removing amino acid residues 105-217 of PPO3 without altering the reading frame. The deletion removes part of the conserved copper-binding domain.

    (Dudzic et al., 2015)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    deletion
    2R:23,065,141..23,065,476 [+]
    Comment:

    Approximate boundaries of deletion reported as a 336 bp deletion that removes 112 amino acid residues (residues 105-217). The mapped feature is a 336 bp deletion whcih removes residues 105-216.

    (Dudzic et al., 2015)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies have a normal lifespan compared to wild-type controls.

        Mutant larvae and adults show melanisation around the wound site after clean needle injury, as occurs in wild type.

        Mutant larvae infested with eggs from the parasitoid wasp Leptopilina boulardi produce a melanized capsule around the wasp egg, as occurs in wild type.

        Mutant larvae show melanisation of crystal cells after heating at 65[o]C for 10 minutes, as occurs in wild-type larvae.

        (Dudzic et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhancer of
        Statement
        Reference

        PPO31 is a non-enhancer of short lived | conditional phenotype of PPO1Δ, PPO2Δ

        (Dudzic et al., 2015)

        PPO31 is a non-enhancer of abnormal immune response phenotype of PPO1Δ, PPO2Δ

        (Dudzic et al., 2015)
        NOT Suppressor of
        Statement
        Reference

        PPO31 is a non-suppressor of short lived | conditional phenotype of PPO1Δ, PPO2Δ

        (Dudzic et al., 2015)

        PPO31 is a non-suppressor of abnormal immune response phenotype of PPO1Δ, PPO2Δ

        (Dudzic et al., 2015)
        Other
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        PPO2Δ PPO31 double mutant larvae infested with eggs from the parasitoid wasp Leptopilina boulardi are unable to produce a melanized capsule around the wasp egg.

        PPO1Δ PPO31 double mutant larvae infested with eggs from the parasitoid wasp Leptopilina boulardi produce a melanized capsule around the wasp egg, as occurs in wild type.

        PPO1Δ PPO31 double mutant larvae show melanisation of crystal cells after heating at 65[o]C for 10 minutes, as occurs in wild-type larvae.

        PPO2Δ PPO31 double mutant larvae do not show melanisation of crystal cells after heating at 65[o]C for 10 minutes, in contrast to wild-type larvae.

        (Dudzic et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (2)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        PPO31
        (Dutra Nunes and Drummond-Barbosa, 2026, Melcarne et al., 2019, Troha et al., 2019, Dudzic et al., 2015)
        PPO3Δ
        (Kenmoku et al., 2017)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)