FlyBase Allele Report: Dmel\Tet[del-CD]

General Information

Symbol

Dmel\Tet^del-CD

Species

D. melanogaster

Name

FlyBase ID

FBal0317028

Feature type

allele

Associated gene

Dmel\Tet

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Zhang et al., 2015)

Progenitor genotype

Cytology

Description

Encodes a putative truncated protein, in which the catalytic domain of Tet is deleted.

(Zhang et al., 2015)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

3L:2,792,710..2,792,737 [-]

Comment:

28 bases replaced with 5 bases in Tet coding region.

Inserted_sequence:

CTCAT

(Zhang et al., 2015)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

majority die during P-stage (with Tet¹)

(Zhang et al., 2015)

majority die during P-stage (with Tet²)

(Zhang et al., 2015)

short lived (with Tet¹)

(Zhang et al., 2015)

short lived (with Tet²)

(Zhang et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Tet²

(Zhang et al., 2015)

Tet¹

(Zhang et al., 2015)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

DMAD^del-CD

(Zhang et al., 2015)

Tet^del-CD

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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