FB2026_02 , released June 18, 2026
Allele: Dmel\RootDEL.UASp.mRFP1
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General Information
Symbol
Dmel\RootDEL.UASp.mRFP1
Species
D. melanogaster
Name
FlyBase ID
FBal0317064
Feature type
allele
Associated gene
Dmel\Root
Associated Insertion(s)
Carried in Construct
P{UASp-RFP-Root.DEL}
Key Links
Transgenic product class
inframe_deletion
(Chen et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Chen et al., 2015)
Mutagen
in vitro construct
(Chen et al., 2015)
Progenitor genotype
Carried in construct
P{UASp-RFP-Root.DEL}
Cytology
Description

UASp regulatory sequences drive expression of a deleted form of Root which lacks the N-terminal 333 amino acids (this deletion includes the Rootletin conserved domain). The protein is tagged at the N-terminal end with 6 copies of mRFP1.

(Chen et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Root
Tagged with
mRFP1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4insc-Mz1407/RootDEL.UASp.mRFP1 partially rescues Root66

      (Chen et al., 2015)
      Fails to rescue

      Scer\GAL4elav-C155/RootDEL.UASp.mRFP1 fails to rescue Root66

      (Chen et al., 2015)
      Comments

      The severe climbing defect of Root66 homozygous adults is not rescued by expression of RootDEL.Scer\UAS.P\T.T:Disc\RFP under the control of Scer\GAL4elav-C155. Slight rescue is seen when RootDEL.Scer\UAS.P\T.T:Disc\RFP is expressed under the control of Scer\GAL4insc-Mz1407.

      The lack of touch sensitivity seen in Root66 homozygous larvae is not rescued by expression of RootDEL.Scer\UAS.P\T.T:Disc\RFP under the control of either Scer\GAL4elav-C155 or Scer\GAL4insc-Mz1407.

      (Chen et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      RootDEL.Scer\UAS.P\T.T:Disc\RFP
      RootDEL.UASp.mRFP1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)