FlyBase Allele Report: Dmel\PIG-A[HMJ23951]

General Information

Symbol

Dmel\PIG-A^HMJ23951

Species

D. melanogaster

Name

FlyBase ID

FBal0317322

Feature type

allele

Associated gene

Dmel\PIG-A

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ23951}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HMJ23951}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ23951

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of multiple congenital anomalies-hypotonia-seizures syndrome 2

CEA

(Thorpe et al., 2025)

CEC

(Thorpe et al., 2024)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of multiple congenital anomalies-hypotonia-seizures syndrome 2

is ameliorated by Cont^HM05134

(Thorpe et al., 2025)

is ameliorated by Cont^HMS00186

(Thorpe et al., 2025)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

bang sensitive, with Scer\GAL4^repo

(Thorpe et al., 2025)

decreased rate of adult locomotory behavior, with Scer\GAL4^GMR71C07

(Thorpe et al., 2025)

decreased size | adult stage, with Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

melanotic necrosis | adult stage, with Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

visible | adult stage, with Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025, Pletcher et al., 2019)

Phenotype Manifest In

eye, with Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025, Pletcher et al., 2019)

Detailed Description

Statement

Reference

Expression under the control of Scer\GAL4^eya.enh1+E+2 results in a glossy eye phenotype.

(Pletcher et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by rt^HMC03363, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by PIG-S^KK115806, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by Zip71B^HMC04064, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by CG32052^HMS03024, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by gny^HMC03439, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by gry^HMJ22898, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by Dpm1^KK102477, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by fng^JF01967, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, enhanceable by PGAP5^GD538, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT Enhanced by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, non-enhanceable by Dpm1^GLC01664, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Suppressed by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, suppressible | partially by Cont^HM05134, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, suppressible | partially by Cont^HMS00186, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, suppressible by Ace^JF01978, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^GMR71C07 has decreased rate of adult locomotory behavior phenotype, suppressible | partially by Cont^HM05134, Scer\GAL4^GMR71C07

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^repo has bang sensitive phenotype, suppressible | partially by Cont^HM05134, Scer\GAL4^repo

(Thorpe et al., 2025)

NOT suppressed by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, non-suppressible by Dpm1^GLC01664, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT Enhancer of

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-enhancer of decreased size | adult stage phenotype of Cont^HM05134, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-enhancer of decreased size | adult stage phenotype of Cont^HMS00186, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^repo is a non-enhancer of abnormal behavior | adult stage phenotype of Cont^HM05134, Scer\GAL4^repo

(Thorpe et al., 2025)

NOT Suppressor of

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^repo is a non-suppressor of abnormal behavior | adult stage phenotype of Cont^HM05134, Scer\GAL4^repo

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-suppressor of decreased size | adult stage phenotype of Cont^HM05134, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-suppressor of decreased size | adult stage phenotype of Cont^HMS00186, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Phenotype Manifest In

Enhanced by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by rt^HMC03363, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by PIG-S^KK115806, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by Zip71B^HMC04064, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by CG32052^HMS03024, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by gny^HMC03439, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by gry^HMJ22898, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by Dpm1^KK102477, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by fng^JF01967, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, enhanceable by PGAP5^GD538, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT Enhanced by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, non-enhanceable by Dpm1^GLC01664, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Suppressed by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, suppressible | partially by Cont^HM05134, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, suppressible | partially by Cont^HMS00186, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, suppressible by Ace^JF01978, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT suppressed by

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 has eye phenotype, non-suppressible by Dpm1^GLC01664, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT Enhancer of

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-enhancer of eye phenotype of Cont^HM05134, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-enhancer of eye phenotype of Cont^HMS00186, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT Suppressor of

Statement

Reference

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-suppressor of eye phenotype of Cont^HM05134, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2 is a non-suppressor of eye phenotype of Cont^HMS00186, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

62696

y¹ v¹; P{TRiP.HMJ23951}attP40/CyO

NIG-Fly

HMJ23951

y¹ v¹; P{TRiP.HMJ23951}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG6401^HMJ23951

PIG-A^HMJ23951

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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