FlyBase Allele Report: Dmel\Cont[HMS00186]

General Information

Symbol

Dmel\Cont^HMS00186

Species

D. melanogaster

Name

FlyBase ID

FBal0263181

Feature type

allele

Associated gene

Dmel\Cont

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00186}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.HMS00186}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00186

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates multiple congenital anomalies-hypotonia-seizures syndrome 2

modeled by PIG-A^HMJ23951

(Thorpe et al., 2025)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Phenotype Manifest In

eye, with Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Cont^HMS00186, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, non-enhanceable by PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT suppressed by

Statement

Reference

Cont^HMS00186, Scer\GAL4^eya.enh1+E+2 has decreased size | adult stage phenotype, non-suppressible by PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Suppressor of

Statement

Reference

Cont^HMS00186, Scer\GAL4^eya.enh1+E+2 is a suppressor | partially of decreased size | adult stage phenotype of PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Cont^HMS00186, Scer\GAL4^eya.enh1+E+2 has eye phenotype, non-enhanceable by PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

NOT suppressed by

Statement

Reference

Cont^HMS00186, Scer\GAL4^eya.enh1+E+2 has eye phenotype, non-suppressible by PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Suppressor of

Statement

Reference

Cont^HMS00186, Scer\GAL4^eya.enh1+E+2 is a suppressor | partially of eye phenotype of PIG-A^HMJ23951, Scer\GAL4^eya.enh1+E+2

(Thorpe et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

34867

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00186}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Cont^HMS00186

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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