FlyBase Allele Report: Dmel\Nsun2[HMJ24019]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\Nsun2^HMJ24019

General Information

Symbol

Dmel\Nsun2^HMJ24019

Species

D. melanogaster

Name

FlyBase ID

FBal0317350

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ24019}

Key Links

Genomic Maps

Transgenic product class

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HMJ24019}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates tauopathy

modeled by Hsap\MAPT^UAS.2N4R.cSa

(Kim et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Nsun2^HMJ24019, Scer\GAL4^GMR.PU is an enhancer of visible | adult stage phenotype of Hsap\MAPT^UAS.2N4R.cSa, Scer\GAL4^GMR.PU

(Kim et al., 2023)

Suppressor of

Statement

Reference

Nsun2^HMJ24019, Scer\GAL4^GMR.PY is a suppressor of visible | adult stage phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

NOT Suppressor of

Statement

Reference

Nsun2^HMJ24019, Scer\GAL4^GMR.PY is a non-suppressor of abnormal size | adult stage phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Phenotype Manifest In

Enhancer of

Statement

Reference

Nsun2^HMJ24019, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\MAPT^UAS.2N4R.cSa, Scer\GAL4^GMR.PU

(Kim et al., 2023)

Suppressor of

Statement

Reference

Nsun2^HMJ24019, Scer\GAL4^GMR.PY is a suppressor of eye phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

NOT Suppressor of

Statement

Reference

Nsun2^HMJ24019, Scer\GAL4^GMR.PY is a non-suppressor of retina | adult stage phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

62495

y¹ v¹; P{TRiP.HMJ24019}attP40/CyO

HMJ24019

y¹ v¹; P{TRiP.HMJ24019}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Nsun2^HMJ24019

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections