FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Fas2UAS.ΔCT.KNSAV.Tag:FLAG
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General Information
Symbol
Dmel\Fas2UAS.ΔCT.KNSAV.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0318351
Feature type
allele
Associated gene
Dmel\Fas2
Associated Insertion(s)
Carried in Construct
P{UAS-Fas2.ΔCT.FLAG.KNSAV}
Key Links
Transgenic product class
Mutagen
    Nature of the Allele
    Transgenic product class
    Mutagen
    Progenitor genotype
    Carried in construct
    P{UAS-Fas2.ΔCT.FLAG.KNSAV}
    Cytology
    Description

    UAS regulatory sequences drive expression of the Fas2 PA isoform in which amino acid residues from 770 to the C-terminus have been deleted. The protein is tagged at the C-terminal end with Tag:FLAG. The Fas2 PDZ binding sequence (KNSAV) has been reinserted following the Tag:FLAG tag, as this sequence is important for Fas2 expression in the mushroom body.

    (Bornstein et al., 2015)
    Allele components
    Component
    Use(s)
    Regulatory region(s)
    UAS
    Encoded product / tool
    Fas2
    Tagged with
    Tag:FLAG
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Overexpression of Fas2Scer\UAS.ΔCT.KNSAV.T:Zzzz\FLAG with Scer\GAL4Tab2-201Y does not inhibit pruning.

        (Bornstein et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Co-expression of bskDN.Scer\UAS.cUa with Fas2Scer\UAS.ΔCT.KNSAV.T:Zzzz\FLAG by Scer\GAL4Tab2-201Y results in mushroom body pruning defects.

        (Bornstein et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Fas2Scer\UAS.ΔCT.KNSAV.T:Zzzz\FLAG
        Fas2UAS.ΔCT.KNSAV.Tag:FLAG
        Name Synonyms
        Secondary FlyBase IDs
          References (1)