The majority of CPT2δ3 animals die during the first 3 days after eclosion - very few die during larval or pupal development. Those that survive the immediate post-eclosion period show a severely reduced adult lifespan and are hyper-sensitive to starvation.
Normally fed CPT2δ3 flies are not heaver, but even lighter than controls. Body length is somewhat reduced, but the ratio of weight and size (BMI) is not increased, compared to controls. Motor activity is also unchanged. However, while total body triacylglyceride (TAG) levels are not increased, there is massive accumulation of TAG-filled lipid droplets in the brains and flight muscle in these mutant flies.