FlyBase Allele Report: Dmel\Tet[null]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Tet^null

General Information

Symbol

Dmel\Tet^null

Species

D. melanogaster

Name

FlyBase ID

FBal0318614

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen

FLPase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Delatte et al., 2016)

Mutagen

(Delatte et al., 2016)

Progenitor genotype

(Delatte et al., 2016)

(Delatte et al., 2016)

Cytology

Description

Deletion removing the 5' end of the Tet gene. Generated by FLP-mediated recombination between the progenitor PBac{WH}f05022 and PBac{WH}f03062 insertions.

(Delatte et al., 2016)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

3L:2,807,704..2,882,251 [-]

Comment:

Inferred boundaries of a deletion generated by FLP-mediated recombination between the progenitor PBac{WH}f05022 and PBac{WH}f03062 insertions, which removes the 5' end of Tet.

(Delatte et al., 2016)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | larval stage (with Tet^MI03920)

(Frey et al., 2022)

abnormal neuroanatomy | adult stage (with Tet^MI03920)

(Frey et al., 2022)

abnormal neuroanatomy | larval stage

(Delatte et al., 2016)

abnormal neuroanatomy | larval stage (with Tet^MI03920)

(Frey et al., 2022)

increased cell death | larval stage (with Tet^MI03920)

(Frey et al., 2022)

increased cell number | adult stage (with Tet^MI03920)

(Frey et al., 2022)

increased cell number | larval stage (with Tet^MI03920)

(Frey et al., 2022)

increased occurrence of cell division | larval stage (with Tet^MI03920)

(Frey et al., 2022)

lethal - all die before end of larval stage

(Frey et al., 2022)

lethal - all die during P-stage

(Delatte et al., 2016)

partially lethal (with Tet^MI03920)

(Frey et al., 2022)

partially lethal (with Tet^{MI04973-TG4.0})

(Frey et al., 2022)

short lived (with Tet^MI03920)

(Frey et al., 2022)

short lived (with Tet^{MI04973-TG4.0})

(Frey et al., 2022)

some die during P-stage (with Tet^MI03920)

(Frey et al., 2022)

Phenotype Manifest In

adult CNS glial cell | increased number (with Tet^MI03920)

(Frey et al., 2022)

adult inner optic chiasma giant glial cell (with Tet^MI03920)

(Frey et al., 2022)

adult mushroom body (with Tet^MI03920)

(Frey et al., 2022)

adult mushroom body beta-lobe (with Tet^MI03920)

(Frey et al., 2022)

commissure | larval stage (with Tet^MI03920)

(Frey et al., 2022)

larval brain | larval stage

(Delatte et al., 2016)

larval brain | larval stage (with Tet^MI03920)

(Frey et al., 2022)

larval glial cell | increased number | larval stage (with Tet^MI03920)

(Frey et al., 2022)

larval ventral nerve cord | larval stage (with Tet^MI03920)

(Frey et al., 2022)

medulla | larval stage

(Delatte et al., 2016)

midline glial cell | larval stage (with Tet^MI03920)

(Frey et al., 2022)

mushroom body vertical lobe (with Tet^MI03920)

(Frey et al., 2022)

Detailed Description

Statement

Reference

The brains of mutant larvae are smaller than normal, the width of the medulla region is significantly reduced.

(Delatte et al., 2016)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

606056

Tet^null/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

TETnull

(Hastert et al., 2025)

Tet^null

(Gerdy et al., 2025, Gilbert et al., 2024, Singh et al., 2024, Tran et al., 2024, Frey et al., 2022, Wang et al., 2018)

dTet^null

(Delatte et al., 2016)

tet^null

(Boulet et al., 2023)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections