FB2026_02 , released June 18, 2026
Allele: Dmel\Gbp2UAS.cKa
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General Information
Symbol
Dmel\Gbp2UAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Koyama
FlyBase ID
FBal0318722
Feature type
allele
Associated gene
Dmel\Gbp2
Associated Insertion(s)
Carried in Construct
P{UAS-Gbp2.K}
Key Links
Transgenic product class
wild_type
(Koyama and Mirth, 2016)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Koyama and Mirth, 2016)
Mutagen
in vitro construct
(Koyama and Mirth, 2016)
Progenitor genotype
Carried in construct
P{UAS-Gbp2.K}
Cytology
Description

UASt regulates expression of the entire open reading frame of Gbp2.

(Koyama and Mirth, 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gbp2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Gbp2Scer\UAS.cKa driven by Scer\GAL4C7 induces slight but significant increases in male and female body size at 25[o]C, and even greater increases at 22[o]C (measured body weight at pharate adult stage).

      (Koyama and Mirth, 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      At 22[o]C, co-expression of Gbp1Scer\UAS.cKa and Gbp2Scer\UAS.cKa driven by Scer\GAL4C7 partially suppresses the body size decreases, slower larval growth rate, and increased duration of the third instar larval stage (L3) seen in Df(2R)Gbp-ex67/Df(2R)Gbp-ex67 (though body size and duration of L3 is still significantly reduced compared to wild type).

      At 22[o]C, co-expression of Gbp2Scer\UAS.cKa partially suppresses the body size decreases, slower larval growth rate, and increased duration of the third instar larval stage (L3) seen in animals with Tsc1Scer\UAS.cUa and gigScer\UAS.cUa driven by Scer\GAL4C7 (though body size, larval growth rate and duration of L3 is still significantly reduced compared to wild type).

      (Koyama and Mirth, 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gbp2Scer\UAS.cKa
      Gbp2UAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Koyama
      Secondary FlyBase IDs
        References (2)