Open Close
General Information
Symbol
Dmel\gigUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0318720
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-TSC2
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulates expression of gig.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of gigUAS.cUa under the control of Scer\GAL4GSG5966 (and RU486 feeding) induces lipid droplet autophagy (dual LS2- and Atg8-positive puncta) in the adult midgut, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Tsc1Scer\UAS.cUa and gigScer\UAS.cUa driven by Scer\GAL4C7 significantly decreases male and female body size (body weight measured at pharate adult stage), significantly decreases larval growth rates and significantly increases the duration of the third instar larval stage.

At 22[o]C, co-expression of Gbp1Scer\UAS.cKa or Gbp2Scer\UAS.cKa partially suppresses the body size decreases, slower larval growth rate, and increased duration of the third instar larval stage (L3) seen in animals with Tsc1Scer\UAS.cUa and gigScer\UAS.cUa driven by Scer\GAL4C7 (though body size, larval growth rate and duration of L3 is still significantly reduced compared to wild type).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
gigScer\UAS.cUa
gigUAS.cUa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Unknown
Secondary FlyBase IDs
    References (5)