FlyBase Allele Report: Dmel\Dlic[RNAi.UAS.cUa]

General Information

Symbol

Dmel\Dlic^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0318825

Feature type

allele

Associated gene

Dmel\Dlic

Associated Insertion(s)

Carried in Construct

P{UAS-Dlic.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Dlic.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of a Dlic RNAi line.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Dlic

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^ppk.PU

(Arthur et al., 2015)

Phenotype Manifest In

dendrite | third instar larval stage, with Scer\GAL4^ppk.PU

(Arthur et al., 2015)

larval multidendritic class IV neuron | third instar larval stage, with Scer\GAL4^ppk.PU

(Arthur et al., 2015)

Detailed Description

Statement

Reference

Expression of Dlic^{dsRNA.Scer\UAS.cUa} (along with UAS-dcr2) driven by Scer\GAL4^ppk.PU significantly affects dendrite morphology (reduces dendrite growth and branching) in third instar larval class IV da neurons compared to controls.

(Arthur et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Dlic^RNAi.UAS.cUa, Scer\GAL4^ppk.PU has abnormal neuroanatomy | third instar larval stage phenotype, enhanceable by nudE^39A/nudE^39A

(Arthur et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Dlic^RNAi.UAS.cUa, Scer\GAL4^ppk.PU has larval multidendritic class IV neuron | third instar larval stage phenotype, enhanceable by nudE^39A/nudE^39A

(Arthur et al., 2015)

Dlic^RNAi.UAS.cUa, Scer\GAL4^ppk.PU has dendrite | third instar larval stage phenotype, enhanceable by nudE^39A/nudE^39A

(Arthur et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

nudE^39A/nudE^39A enhances dendrite morphology defects in class IV da neurons of third instar larvae with expression of Dlic^{dsRNA.Scer\UAS.cUa} (along with UAS-dcr2) driven by Scer\GAL4^ppk.PU.

(Arthur et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dlic^RNAi.UAS.cUa

Dlic^{dsRNA.Scer\UAS.cUa}

Dlic^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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