FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ShawnTag:HA
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General Information
Symbol
Dmel\ShawnTag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0319306
Feature type
allele
Associated gene
Dmel\Shawn
Associated Insertion(s)
Carried in Construct
P{Shawn.HA}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Slabbaert et al., 2016)
wild_type
(Slabbaert et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Slabbaert et al., 2016)
wild_type
(Slabbaert et al., 2016)
Mutagen
in vitro construct
(Slabbaert et al., 2016)
Progenitor genotype
Carried in construct
P{Shawn.HA}
Cytology
Description

Genomic fragment encompassing the bicistronic locus that encodes Shawn and Tyler (derived from BAC clone CH321-35A10). The Shawn open reading frame is tagged at the C-terminal end with Tag:HA.

(Slabbaert et al., 2016)
Allele components
Component
Use(s)
Encoded product / tool
Shawn
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
X:19,610,414..19,616,413 [+]
Comment:

The ~6 kb genomic rescue fragment contains the entire Tyler and Shawn discistronic gene region and a C-terminal HA tag. The position of the genomic rescue fragment on the reference sequence was inferred from reported primer sequences.

(Slabbaert et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ShawnTag:HA rescues Shawn1/Shawn2

      (Slabbaert et al., 2016)

      ShawnTag:HA rescues Shawn1

      (Slabbaert et al., 2016)

      ShawnTag:HA rescues Shawn2

      (Slabbaert et al., 2016)

      ShawnTag:HA rescues ShawnΔ6.3

      (Slabbaert et al., 2016)
      Comments

      ShawnT:Ivir\HA1 rescues lethality in ShawnΔ6.3/ShawnΔ6.3, Shawn1/Shawn1 or Shawn2/Shawn2 mutants. ShawnT:Ivir\HA1 rescues ERG defects, mitochondrial morphology and neuronal degeneration in Shawn1/Shawn1 or Shawn2/Shawn2 full mutant eye clones. ShawnT:Ivir\HA1 rescues increases in EJC amplitude at the NMJ of Shawn1/Shawn2 third instar larvae.

      (Slabbaert et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ShawnT:Ivir\HA1
      ShawnTag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)