FB2025_01 , released February 20, 2025
Allele: Dmel\ZyxUAS.cGa
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General Information
Symbol
Dmel\ZyxUAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Gaspar
FlyBase ID
FBal0319348
Feature type
allele
Associated gene
Dmel\Zyx
Associated Insertion(s)
Carried in Construct
PBac{UAS-Zyx.G}
Key Links
Transgenic product class
cDNA
(Gaspar et al., 2015)
wild_type
(Gaspar et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Gaspar et al., 2015)
wild_type
(Gaspar et al., 2015)
Mutagen
in vitro construct
(Gaspar et al., 2015)
Progenitor genotype
Carried in construct
PBac{UAS-Zyx.G}
Cytology
Description

UAS regulatory sequences drive expression of the Zyx LD06023 cDNA.

(Gaspar et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Zyx
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of ZyxScer\UAS.cGa under the control of Scer\GAL4nub.PU results in significantly larger wings in adult flies.

      Eyes of adult flies expressing ZyxScer\UAS.cGa under the control of Scer\GAL4GMR.PU do not have the smooth eye surface like the wild-type flies.

      (Gaspar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4nub.PU/ZyxUAS.cGa is a non-suppressor of wing blade phenotype of Scer\GAL4nub.PU, wtsUAS.L.Tag:MYC

      (Gaspar et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The severely undergrown wing phenotype seen in adult flies expressing ftΔECD.Scer\UAS under the control of Scer\GAL4nub.PU can be mildly alleviated by co-expression of ZyxScer\UAS.cGa.

      The severely undergrown wing phenotype seen in adult flies expressing exScer\UAS.cBa under the control of Scer\GAL4nub.PU can be strongly alleviated by co-expression of ZyxScer\UAS.cGa.

      The severely undergrown wing phenotype seen in adult flies expressing wtsScer\UAS.L.T:Hsap\MYC under the control of Scer\GAL4nub.PU cannot be alleviated by co-expression of ZyxScer\UAS.cGa.

      (Gaspar et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4nub.PU/ZyxUAS.cGa rescues ZyxΔ41

      (Gaspar et al., 2015)
      Comments

      The small wing phenotype displayed by ZyxΔ41/ZyxΔ41 adults can be fully rescued by expression of ZyxScer\UAS.cGa under the control of Scer\GAL4nub.PU in the mutant background, resulting in adult wings comparable in size to wild-type.

      (Gaspar et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ZyxScer\UAS.cGa
      ZyxUAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Gaspar
      Secondary FlyBase IDs
        References (1)