FlyBase Allele Report: Dmel\wcy[+tGR]

General Information

Symbol

Dmel\wcy^+tGR

Species

D. melanogaster

Name

FlyBase ID

FBal0319612

Feature type

allele

Associated gene

Dmel\wcy

Associated Insertion(s)

Carried in Construct

PBac{wcy.gr}

Key Links

Transgenic product class

genomic_DNA

(David-Morrison et al., 2016)

wild_type

(David-Morrison et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(David-Morrison et al., 2016)

wild_type

(David-Morrison et al., 2016)

Mutagen

in vitro construct

(David-Morrison et al., 2016)

Progenitor genotype

Carried in construct

PBac{wcy.gr}

Cytology

Description

A genomic rescue construct containing wcy genomic sequence with additional 2400 base pairs both upstream and downstream, obtained from the bacterial artificial chromosome clone CH321-45K19.

(David-Morrison et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

wcy

Encoded product / tool

wcy

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

wcy^+tGR rescues wcy^A

(David-Morrison et al., 2016)

wcy^+tGR rescues wcy^B

(David-Morrison et al., 2016)

wcy^+tGR rescues wcy^C

(David-Morrison et al., 2016)

wcy^+tGR rescues wcy^D

(David-Morrison et al., 2016)

wcy^+tGR rescues wcy^F

(David-Morrison et al., 2016)

Comments

wcy^+tGR rescues lethality in wcy^A/wcy^A, wcy^B/wcy^B, wcy^C/wcy^C, wcy^D/wcy^D or wcy^F/wcy^F mutants. wcy^+tGR rescues retinal morphology and electroretinogram defects in wcy^A/wcy^A mutants and rescues electroretinogram defects in wcy^B/wcy^B or wcy^C/wcy^C mutants. wcy^+tGR rescues starvation induced autophagy defects in wcy^A/wcy^A third instar larval fat body clones. wcy^+tGR rescues the programmed autophagy phenotype in wcy^A/wcy^A third instar larval fat body clones.

(David-Morrison et al., 2016)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

wcy^+tGR

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close