FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tret1Tag:HA
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General Information
Symbol
Dmel\Tret1Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0319691
Feature type
allele
Associated gene
Dmel\Tret1
Associated Insertion(s)
Carried in Construct
P{Tret1.HA}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Volkenhoff et al., 2015)
wild_type
(Volkenhoff et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Volkenhoff et al., 2015)
wild_type
(Volkenhoff et al., 2015)
Mutagen
in vitro construct
(Volkenhoff et al., 2015)
Progenitor genotype
Carried in construct
P{Tret1.HA}
Cytology
Description

Genomic fragment that encompasses Tret1-1. Three copies of the Tag:HA tag have been inserted at the C-terminal end of the Tret1-1 coding sequence.

(Volkenhoff et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
Tret1
Encoded product / tool
Tret1
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2R:11,660,494..11,677,935 [+]
Comment:

Genomic region containing Tret1-1 used for rescue. The inserted Plasmid includes a mini-white gene and the genomic region of Tret1-1 with an added 3x HA-tag at the C-terminus (sequence: ATGGATCTCCACCGCGGTGGAGGCCGCATCTTTTACCCATACGATGTTCCTGACTATGCGGGCTATCCCTATGACGTCCCGGACTATGCAGGATCCTATCCATATGACGTTCCAGATTACGCTGCTCATGGCGGA).

(Schirmeier, 2017.4.25)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      second instar larval stage -- third instar larval stage
      larval central nervous system | restricted
      (Volkenhoff et al., 2015)
      third instar larval stage
      embryonic/larval CNS perineurial glial cell
      (Volkenhoff et al., 2015)
      embryonic/larval fat body
      (Volkenhoff et al., 2015)
      adult stage
      adult CNS glial cell
      (Volkenhoff et al., 2015)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Tret1
      (Volkenhoff et al., 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Df(2R)ΔTret, Tret1Tag:HA has flightless phenotype

      (Volkenhoff et al., 2015)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Tret1-1T:Ivir\HA1 rescues lethality in Df(2R)ΔTret/Df(2R)ΔTret mutants; resulting flies are flightless.

      (Volkenhoff et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Tret1-1T:Ivir\HA1
      Tret1-1Tag:HA
      Tret1Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)