FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mopmut.UAS
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General Information
Symbol
Dmel\mopmut.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0319804
Feature type
allele
Associated gene
Dmel\mop
Associated Insertion(s)
Carried in Construct
P{UAS-mop.mut}
PBac{UAS-mop.mut}
Key Links
Transgenic product class
inframe_deletion
(Loncle et al., 2015)
missense_variant
(Loncle et al., 2015)
Mutagen
    Nature of the Allele
    Transgenic product class
    inframe_deletion
    (Loncle et al., 2015)
    missense_variant
    (Loncle et al., 2015)
    Mutagen
    Progenitor genotype
    Carried in construct
    P{UAS-mop.mut}
    PBac{UAS-mop.mut}
    Cytology
    Description

    UAS regulatory sequences drive expression of a mutated Bro-domain of mop (amino acid residues 1-389) that carries the amino acid replacements I201D and V205D.

    (Loncle et al., 2015)
    Allele components
    Component
    Use(s)
    Regulatory region(s)
    UAS
    Encoded product / tool
    mop
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of mopmut.Scer\UAS driven in the class IV dendritic arborizing sensory neuron ddaC by Scer\GAL4ppk.1.9 does not lead to pruning defects at 18hr after puparium formation.

        (Loncle et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to rescue

        Scer\GAL4ppk.1.9/mopmut.UAS fails to rescue mopHM05008

        (Loncle et al., 2015)
        Comments

        Co-expression of mopWD.Scer\UAS (but not mopmut.Scer\UAS) rescues dendrite pruning defects seen when mopHMS00706 is driven in the class IV dendritic arborizing sensory neuron ddaC by Scer\GAL4ppk.1.9 at 18hr after puparium formation.

        (Loncle et al., 2015)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        mopmut.Scer\UAS
        mopmut.UAS
        Name Synonyms
        Secondary FlyBase IDs
          References (2)