FB2026_02 , released June 18, 2026
Allele: Dmel\ZyxΔ208-231.UAS
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General Information
Symbol
Dmel\ZyxΔ208-231.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0319824
Feature type
allele
Associated gene
Dmel\Zyx
Associated Insertion(s)
Carried in Construct
PBac{UAS-Zyx.Δ208-231}
Key Links
Transgenic product class
inframe_deletion
(Gaspar et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Gaspar et al., 2015)
Mutagen
in vitro construct
(Gaspar et al., 2015)
Progenitor genotype
Carried in construct
PBac{UAS-Zyx.Δ208-231}
Cytology
Description

UAS regulatory sequences drive expression of Zyx lacking the LPPPP motif (amino acid residues 208-231 are deleted).

(Gaspar et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Zyx
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of ZyxΔ208-231.Scer\UAS under the control of Scer\GAL4nub.PU results in slightly but significantly smaller adult wings compared to wild-type.

      (Gaspar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The severely undergrown wing phenotype seen in adult flies expressing exScer\UAS.cBa under the control of Scer\GAL4nub.PU cannot be suppressed by co-expression of ZyxΔ208-231.Scer\UAS : the wings of flies expressing both exScer\UAS.cBa and ZyxΔ208-231.Scer\UAS are even smaller than those of animals expressing exScer\UAS.cBa alone, the wing blade being lost altogether.

      (Gaspar et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ZyxΔ208-231.UAS/Scer\GAL4nub.PU rescues ZyxΔ41

      (Gaspar et al., 2015)
      Comments

      The small wing phenotype displayed by ZyxΔ41/ZyxΔ41 adults can be fully rescued by expression of ZyxΔ208-231.Scer\UAS under the control of Scer\GAL4nub.PU in the mutant background, resulting in adult wings that are comparable in size to wild-type.

      (Gaspar et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ZyxΔ208-231.Scer\UAS
      ZyxΔ208-231.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)