FlyBase Allele Report: Dmel\U2A[hs.PW]

General Information

Symbol

Dmel\U2A^hs.PW

Species

D. melanogaster

Name

heat shock construct of Wu

FlyBase ID

FBal0319836

Feature type

allele

Associated gene

Dmel\U2A

Associated Insertion(s)

Carried in Construct

P{hs-U2A.W}

Key Links

Transgenic product class

wild_type

(Wu et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Wu et al., 2016)

Mutagen

in vitro construct

(Wu et al., 2016)

Progenitor genotype

Carried in construct

P{hs-U2A.W}

Cytology

Description

Hsp70 promoter sequences drive expression of U2A.

(Wu et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

U2A

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | temperature conditional, with U2A^1.W

(Wu et al., 2016)

male sterile | temperature conditional, with U2A^1.W

(Wu et al., 2016)

Phenotype Manifest In

spermatocyte cyst | temperature conditional, with U2A^1.W

(Wu et al., 2016)

spermatogonium | temperature conditional, with U2A^1.W

(Wu et al., 2016)

spermatozoon | temperature conditional, with U2A^1.W

(Wu et al., 2016)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

U2A^hs.PW rescues U2A^1.W

(Wu et al., 2016)

Comments

Continuous heat shock treatment with U2A^hs.PW rescues lethality of U2A^1.W/U2A^1.W, allowing survival to adulthood.

(Wu et al., 2016)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

U2A^hs.PW

Name Synonyms

heat shock construct of Wu

Secondary FlyBase IDs

References (1)

Report Sections

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