FlyBase Allele Report: Dmel\Pph13[hs.PL]

General Information

Symbol

Dmel\Pph13^hs.PL

Species

D. melanogaster

Name

heat shock construct of Liang

FlyBase ID

FBal0319846

Feature type

allele

Associated gene

Dmel\Pph13

Associated Insertion(s)

Carried in Construct

P{hs-Pph13.PL}

Key Links

Transgenic product class

cDNA

(Liang et al., 2016)

wild_type

(Liang et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Liang et al., 2016)

wild_type

(Liang et al., 2016)

Mutagen

in vitro construct

(Liang et al., 2016)

Progenitor genotype

Carried in construct

P{hs-Pph13.PL}

Cytology

Description

An Hsp70 promoter drive expression of a Pph13 cDNA.

(Liang et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

Pph13

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Pph13^hs.PL is a non-suppressor of visible | adult stage phenotype of gl³

(Liang et al., 2016)

Pph13^hs.PL is a non-suppressor of visible | adult stage phenotype of gl^60j

(Liang et al., 2016)

Phenotype Manifest In

Suppressor of

Statement

Reference

Pph13^hs.PL is a suppressor of eye photoreceptor cell | P-stage phenotype of gl³

(Liang et al., 2016)

Pph13^hs.PL is a suppressor of rhabdomere phenotype of gl³

(Liang et al., 2016)

Pph13^hs.PL is a suppressor of ommatidium | P-stage phenotype of gl³

(Liang et al., 2016)

gl^hs.PL/Pph13^hs.PL is a suppressor of eye photoreceptor cell | P-stage phenotype of gl^60j

(Liang et al., 2016)

gl^hs.PL/Pph13^hs.PL is a suppressor of rhabdomere phenotype of gl^60j

(Liang et al., 2016)

NOT Suppressor of

Statement

Reference

Pph13^hs.PL is a non-suppressor of eye phenotype of gl³

(Liang et al., 2016)

Pph13^hs.PL is a non-suppressor of eye photoreceptor cell | P-stage phenotype of gl^60j

(Liang et al., 2016)

Pph13^hs.PL is a non-suppressor of eye phenotype of gl^60j

(Liang et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Pulsing Pph13^hs.PL expression using heat shocks rescues photoreceptor differentiation in gl³/gl³ mutant (but not gl^60j/gl^60j mutant) retinas, as indicated by the presence of definable rhabdomeres at 96 h APF, but does not further disrupt or rescue overall eye morphology of gl³/gl³ or gl^60j/gl^60j mutants.

Pulsing expression of both Pph13^hs.PL and gl^hs.PL using heat shocks restores photoreceptor differentiation in gl^60j/gl^60j mutant) retinas, as indicated by the presence of definable rhabdomeres at 96 h APF.

(Liang et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Pph13^hs.PL

Name Synonyms

heat shock construct of Liang

Secondary FlyBase IDs

References (1)

Report Sections

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