FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Letm1UAS.cHa
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General Information
Symbol
Dmel\Letm1UAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Huang
FlyBase ID
FBal0319981
Feature type
allele
Associated gene
Dmel\Letm1
Associated Insertion(s)
Carried in Construct
P{UAS-Letm1.H}
Key Links
Transgenic product class
cDNA
(Huang et al., 2016)
wild_type
(Huang et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Huang et al., 2016)
wild_type
(Huang et al., 2016)
Mutagen
in vitro construct
(Huang et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Letm1.H}
Cytology
Description

UAS drives expression of the Letm1 EST clone GH03311.

(Huang et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Letm1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  neurodegenerative disease
      modeled by trpP365
      (Huang et al., 2016)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Letm1Scer\UAS.cHa driven by Scer\GAL4GMR.PF does not cause retinal cell death.

      (Huang et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Letm1Scer\UAS.cHa driven by Scer\GAL4GMR.PF enhances retinal degeneration (loss of rhabdomeres from photoreceptors) in 5 day old trpP365/+ flies.

      (Huang et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Letm1Scer\UAS.cHa
      Letm1UAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Huang
      Secondary FlyBase IDs
        References (1)