FB2026_02 , released June 18, 2026
Allele: Dmel\Tps1TPS
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General Information
Symbol
Dmel\Tps1TPS
Species
D. melanogaster
Name
FlyBase ID
FBal0321688
Feature type
allele
Associated gene
Dmel\Tps1
Associated Insertion(s)
Carried in Construct
P{Tps1.TPS}
Key Links
Transgenic product class
stop_gained
(Yoshida et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
stop_gained
(Yoshida et al., 2016)
Mutagen
in vitro construct
(Yoshida et al., 2016)
Progenitor genotype
Carried in construct
P{Tps1.TPS}
Cytology
Description

Genomic fragment containing the Tps1 transcription unit. A stop codon has been introduced before the trehalose-6-phosphate phosphatase (TPP) domain, resulting in a protein consisting of only the trehalose-6-phosphate synthase (TPS) domain.

(Yoshida et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
Tps1
Encoded product / tool
Tps1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Tps1TPS fails to rescue Tps1d2

      (Yoshida et al., 2016)
      Comments

      Expression of Tps1TPS fails to rescue the lethality and the decreased circulating glucose and trehalose levels observed in Tps1d2/Tps1d2 mutants.

      (Yoshida et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Tps1TPS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)