FlyBase Allele Report: Dmel\eIF4B[VSH330010]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\eIF4B^VSH330010

General Information

Symbol

Dmel\eIF4B^VSH330010

Species

D. melanogaster

Name

FlyBase ID

FBal0324389

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

Transgenic product class

(Meadows, 2017.1.11)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Meadows, 2017.1.11)

Mutagen

in vitro construct

(Meadows, 2017.1.11)

Progenitor genotype

Carried in construct

Cytology

Description

UAS regulatory sequences drive expression of a short hairpin microRNA (shRNA).

(Meadows, 2017.1.11)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

dsRNA-VSH330010

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates C9orf72 frontotemporal dementia and/or amyotrophic lateral sclerosis

modeled by Zzzz\GGGGCC^{44.LDS.UAS.GR-GFP}

(Goodman et al., 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/eIF4B^VSH330010 is a suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\GGGGCC^{44.LDS.UAS.GR-GFP}

(Goodman et al., 2019)

Scer\GAL4^GMR.PF/eIF4B^VSH330010 is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\GGGGCC^{44.LDS.UAS.GR-GFP}

(Goodman et al., 2019)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/eIF4B^VSH330010 is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, Zzzz\GGGGCC^{44.LDS.UAS.GR-GFP}

(Goodman et al., 2019)

Scer\GAL4^GMR.PF/eIF4B^VSH330010 is a suppressor of retina phenotype of Scer\GAL4^GMR.PF, Zzzz\GGGGCC^{44.LDS.UAS.GR-GFP}

(Goodman et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

v330010

P{VSH330010}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

330010

(Meadows, 2017.1.11)

eIF4B^VSH330010

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections