FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nanGAL4
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General Information
Symbol
Dmel\nanGAL4
Species
D. melanogaster
Name
FlyBase ID
FBal0324687
Feature type
allele
Associated gene
Dmel\nan
Associated Insertion(s)
TI{TI}nanGAL4
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Jeong et al., 2016)
Mutagen
ends-out gene targeting
(Jeong et al., 2016)
Progenitor genotype
Associated Insertion(s)
TI{TI}nanGAL4
Cytology
Description

Part of the nan locus has been replaced by Scer\GAL4 and mini-w; the inserted Scer\GAL4 sequence is not expressed.

(Jeong et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      chordotonal neuron of head
      (Zhang et al., 2020)
      external sensory organ of head
      (Zhang et al., 2020)
      mouth hook | vicinity of
      (Zhang et al., 2020)
      Additional Information
      Statement
      Reference

      Nine neurons were labeled by the nan reporter in each hemi-segment and 6 of them were co-labelled with iav-Gal4. Among these 6 neurons, one was located in thoracic internal organs, one under the mouth hook, one in the mouth that may belong to the labial organ, two in the terminal organ, and one in the dorsolateral part of the terminal organ and are identified as chordotonal neurons. The remaining three neurons are separately located in the terminal organ, dorsal organ, and ventral organ and are likely es organ neurons.

      (Zhang et al., 2020)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      nanGAL4 larvae show decreased head-touch response.

      (Zhang et al., 2020)

      nanGAL4 mutant adults show defects in sensing food hardness and in contrast to wild-type display diminished preference for softer food with lower sugar content (0.5mM sucrose, 0.2% agarose) to a hard food with higher sugar content (1mM sucrose, 2% agarose) in a binary choice assay.

      (Jeong et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nanGAL4
      (Luedke et al., 2024, Tian et al., 2022, Jeong et al., 2016)
      nanGal4
      (Zhang et al., 2020, Zhang et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)