FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\garzUAS.cUa
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General Information
Symbol
Dmel\garzUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0324960
Feature type
allele
Associated gene
Dmel\garz
Associated Insertion(s)
Carried in Construct
P{UAS-garz.U}
Key Links
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{UAS-garz.U}
Cytology
Description

UAS regulatory sequences drive expression of garz.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
garz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adult flies expressing garzScer\UAS.cUa under the control of Scer\GAL4ninaE.PU show an abnormal drop in the number of rhodopsin1-containing vesicles per ommatidium during illumination.

      (Thakur et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Suppressor of
      Statement
      Reference

      Scer\GAL4ninaE.PU/garzUAS.cUa is a suppressor of retina | adult stage | progressive | conditional phenotype of Pld3.1

      (Thakur et al., 2016)

      Scer\GAL4ninaE.PU/garzUAS.cUa is a suppressor of ommatidium | adult stage | progressive | conditional phenotype of Pld3.1

      (Thakur et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The abnormal drop in the number of rhodopsin1-containing vesicles per ommatidium during illumination seen in adult flies expressing garzScer\UAS.cUa under the control of Scer\GAL4ninaE.PU is partially rescued by co-expression of Vps35dsRNA.Scer\UAS.cUa (together with UAS-Dicer2 to enhance RNAi efficiency).

      The light-dependent retinal degeneration observed in Pld3.1 homozygous adults is suppressed by combination with laza22 (in homozygous state) or by expression of garzScer\UAS.cUa under the control of Scer\GAL4ninaE.PU in the mutant background.

      The abnormal drop in the number of rhodopsin1-containing vesicles per ommatidium upon illumination observed in adult flies expressing PldScer\UAS.cRa under the control of Scer\GAL4ninaE.PU is fully suppressed by co-expression of garzGD13940 (together with UAS-Dicer2 to enhance the RNAi efficiency).

      (Thakur et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      garzScer\UAS.cUa
      garzUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (2)