FB2026_03 , released September 17, 2026
Allele: Dmel\Ubr3RINGmut.UAS.Tag:FLAG
Open Close
General Information
Symbol
Dmel\Ubr3RINGmut.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0324993
Feature type
allele
Associated gene
Dmel\Ubr3
Associated Insertion(s)
Carried in Construct
PBac{UAS-Ubr3.RINGmut.FLAG}
Key Links
Transgenic product class
missense_variant
(Li et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Li et al., 2016)
Mutagen
in vitro construct
(Li et al., 2016)
Progenitor genotype
Carried in construct
PBac{UAS-Ubr3.RINGmut.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of an E3 dead form of Ubr3 cDNA (the residues required for RING domain activity are mutated to alanines) fused to a Tag:FLAG tag at the C-terminus.

(Li et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ubr3
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4Act.PU/Ubr3RINGmut.UAS.Tag:FLAG fails to rescue Ubr3B

      (Li et al., 2016)
      Comments

      The detached scolopidia phenotype observed in pupae bearing Ubr3B mutant clones in the Johnston's organ cannot be rescued by expression of Ubr3RINGmut.Scer\UAS.T:Zzzz\FLAG driven by Scer\GAL4Act.PU in the mutant cells.

      (Li et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ubr3RINGmut.Scer\UAS.T:Zzzz\FLAG
      Ubr3RINGmut.UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)