FB2026_02 , released June 18, 2026
Allele: Dana\dsx+t21E22
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General Information
Symbol
Dana\dsx+t21E22
Species
D. ananassae
Name
FlyBase ID
FBal0325114
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Dana\dsx BAC clone (r1.3 scaffold_13340:14858455..14908776 , clone address 21E22).

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

Dana\dsx+t21E22 is a non-suppressor of sterile phenotype of dsxΔ

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The intersex phenotype of dsxΔ/dsxΔ flies can be rescued by combination with either Dana\dsx+t21E22 (the morphology of external genitalia and penis of the xenotransgenic rescue males is comparable to males rescued with a wild-type D. melanogaster dsx transgene, only minor defects in sex comb formation are observed), however it fails to rescue the dsxΔ mutant sterility.

The xenotransgene also rescues the courtship behavior of dsxΔ mutants without imparting any of the unique species-specific courtship behavior but also without transferring the quantitative differences in aspects of the courtship behavior that are shared between the species (e.g. the time spent with wings extended or the angle of the wing relative to the body axis). The xenotransgenic rescue males also do not show species-specific song interconversion but sing like Drosophila melanogaster with alternating bouts of pulse and sine song.

dsx1 fruP1.LexA/dsxΔ fruAJ96u3 double mutants rescued with Dana\dsx+t21E22 and Dana\fru+t20H8 also sing like melanogaster with both pulse and sine song elements present, whereas mutants rescued with Dper\dsx+t31M5 and Dper\fru+t36N18 only sing normal-pulse song but not the sine song (but still do not display any evidence of species-specific song interconversion).

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Dana\dsx+t21E22
Name Synonyms
Secondary FlyBase IDs
    References (1)