FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Poc1UAS.B.GFP
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General Information
Symbol
Dmel\Poc1UAS.B.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0325418
Feature type
allele
Associated gene
Dmel\Poc1
Associated Insertion(s)
Carried in Construct
P{UAS-Poc1.B.GFP}
Key Links
Transgenic product class
wild_type
(Khire et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Khire et al., 2016)
Mutagen
in vitro construct
(Khire et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Poc1.B.GFP}
Cytology
Description

UAS regulatory sequences drive expression of the coding sequence of the Poc1 B isoform that is tagged at the C-terminal end with GFP.

(Khire et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Poc1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Poc1UAS.B.GFP under the control of Scer\GAL4VP16.bam does not lead to the formation of the procentriolar ectopic particles in mature primary spermatocytes when compared to controls.

      (Jo et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Poc1UAS.B.GFP (under the control of Scer\GAL4VP16.bam) in combination with Sas-6Ubi.P.GFP but not ana2Ubi.C.GFP leads to the formation of the procentriolar ectopic particles in mature primary spermatocytes when compared to controls. Procentriolar ectopic particles in mature primary spermatocytes resemble the proximal centriole-like ultrastructure with tubule-like structures and electron-dense material.

      (Jo et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Poc1UAS.B.GFP, Poc1UAS.A.GFP, Scer\GAL4bam.PU rescues Poc1W87X

      (Khire et al., 2016)
      Fails to rescue

      Poc1UAS.B.GFP/Scer\GAL4bam.PU fails to rescue Poc1W87X

      (Khire et al., 2016)
      Comments

      Expression of Poc1UAS.B.GFP alone under the control of Scer\GAL4bam.PU in the Poc1W87X mutant background does not rescue either the sperm motility defect or the reduced size of the giant centriole in the sperm cells characteristic for Poc1W87X males. Simultaneous expression of both Poc1UAS.A.GFP and Poc1UAS.B.GFP using the same driver rescues both phenotypes.

      (Khire et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Poc1Scer\UAS.B.T:Avic\GFP
      Poc1UAS.B.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)