FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Kdm5Tag:HA
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General Information
Symbol
Dmel\Kdm5Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0325457
Feature type
allele
Associated gene
Dmel\Kdm5
Associated Insertion(s)
Carried in Construct
M{Kdm5-HA}
Also Known As
kdm5WT, gKDM5:HAWT, KDM5:HA
Key Links
Transgenic product class
genomic_DNA
(Navarro-Costa et al., 2016)
wild_type
(Navarro-Costa et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Navarro-Costa et al., 2016)
wild_type
(Navarro-Costa et al., 2016)
Mutagen
in vitro construct
(Navarro-Costa et al., 2016)
Progenitor genotype
Carried in construct
M{Kdm5-HA}
Cytology
Description

An 11.4kb wild-type lid genomic transgene including the lid promoter, tagged at the C-terminal with 3x-Tag:HA.

(Navarro-Costa et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
Kdm5
Encoded product / tool
Kdm5
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult brain | restricted
      (Zamurrad et al., 2018)
      adult pars intercerebralis
      (Zamurrad et al., 2018)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Kdm5
      (Zamurrad et al., 2018)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      lidTag:HA individuals show robust olfactory learning and memory in an appetitive associative olfactory learning assay (at 5min and 9h) but show an apparently normal odor acuity and the expected preference to a sucrose solution over water. These individuals also show normal mushroom body neuropil morphology.

      (Zamurrad et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      FBal0325457:, Kdm5140 is rescued by Kdm5Tag:HA/Kdm5Tag:HA

      (Belalcazar et al., 2021)
      Rescues

      Kdm5Tag:HA/Kdm5Tag:HA rescues FBal0325457:, Kdm5140

      (Belalcazar et al., 2021)

      Kdm5Tag:HA rescues Kdm5140

      (Drelon et al., 2018)

      Kdm5Tag:HA rescues Kdm5k06801/Kdm510424

      (Navarro-Costa et al., 2016)
      Comments

      The premature transcriptional reactivation as well as precocious karyosome remodeling (the oocytes display early increase in chromatin openness) in prophase I-arrested lid10424/lidk06801 transheterozygous oocytes is rescued by combination with lidT:Ivir\HA1.

      (Navarro-Costa et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Kdm5Tag:HA
      Kdm5WT
      (Yheskel et al., 2025, Yheskel et al., 2024)
      kdm5WT
      (Belalcazar et al., 2021)
      lidT:Ivir\HA1
      lidTag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (10)